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5E: Thermodynamics & Kinetics

Card1 / 322
Question

What does Vextmax​ mean, and what MCAT clue matters?

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Answer

Maximum rate at saturating substrate; depends on enzyme amount and catalytic turnover.

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Question

What does Km​ mean, and what MCAT clue matters?

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Answer

[S] when v=Vextmax​/2; lower Km​ often means higher apparent affinity.

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Question

If one enzyme has a hyperbolic v vs. [S] curve and another has a sigmoidal curve, which is more likely allosteric?

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Answer

The sigmoidal enzyme; sigmoidal kinetics suggest cooperativity.

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Question

What does kcat​ mean, and what MCAT clue matters?

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Answer

Turnover number; product formed per enzyme per time at saturation.

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