3A: Nervous & Endocrine Systems

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Question

What is the first event after a ligand binds a GPCR?

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Answer

The receptor changes conformation.

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Question

Thyroid hormone vs. catecholamines: how do these two amino-acid-derived hormones differ mechanistically?

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Answer

Thyroid hormone is lipophilic and intracellular; catecholamines are hydrophilic and use surface .

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Question

Which fat-soluble vitamin named here is a steroid derivative rather than a terpenoid?

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Answer

Vitamin D.

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Question

What structural feature defines a steroid?

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Answer

A four-ring steroid nucleus: three six-membered and one five-membered fused rings.

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