2A: Membranes & Organelles

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Question

If phospholipid synthesis in the ER is blocked, what cellular function is most directly impaired?

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Answer

Membrane biosynthesis and trafficking; fewer membranes and vesicles can form.

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Question

A protein sequence contains a 22-amino-acid stretch dominated by leucine, isoleucine, valine, and phenylalanine. Where is this region likely located?

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Answer

A transmembrane domain; a long hydrophobic segment can span the bilayer as an alpha helix.

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Question

If a cell has linear chromosomes in a nucleus, mitochondria, and a mitotic spindle, how should you classify it?

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Answer

Eukaryotic; all three are hallmark eukaryotic features.

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Question

Fluid mosaic model

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Answer

Mobile lipids and proteins in a bilayer; clue: lateral movement and fluidity.

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