5D: Reactivity & Functional Groups · Flashcards

Question

What does $N a B H_{4}$ reduce that $L i A l H_{4}$ also reduces?

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Answer

Aldehydes and ketones.

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Question

Why is sucrose non-reducing?

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Answer

Its bond joins both anomeric carbons, so neither ring can open.

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Question

How does $L i A l H_{4}$ differ from $N a B H_{4}$ in carbonyl reductions?

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Answer

$L i A l H_{4}$ also reduces acids, esters, and amides; $N a B H_{4}$ does not.

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Question

$b e t a$ -mercaptoethanol/DTT vs heat: how do these reducing agents denature proteins?

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Answer

They reduce disulfide bonds, not by heating.

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